The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2005
Filed:
Sep. 10, 2003
Applicants:
Cécile Combeau, Fontenay aux Roses, FR;
Patrick Mailliet, Fontenay sous Bois, FR;
Marielle Chiron, Paris, FR;
Inventors:
Cécile Combeau, Fontenay aux Roses, FR;
Patrick Mailliet, Fontenay sous Bois, FR;
Marielle Chiron, Paris, FR;
Assignee:
Aventis Pharma S. A., Antony, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/4015 ; A61K031/404 ; C07D209/04 ;
U.S. Cl.
CPC ...
Abstract
The invention relates to compounds of formula (I)in which Ris chosen from the group consisting of:in which Ris a C-Calkyl groupin which X may be Cl, Br, or Fin which n is between 1 and 3, in the E or Z form, or a mixture of the two isomeric forms, possessing antimitotic, antiproliferative and antivascular properties through inhibition of the polymerization of tubulin into microtubules