The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 16, 2005

Filed:

Jun. 22, 2001
Applicants:

Akihiro Fujii, Tokyo, JP;

Hiroshi Tanaka, Tokyo, JP;

Makio Otsuki, Tokyo, JP;

Takafumi Kawaguchi, Tokyo, JP;

Kouichi Oshita, Tokyo, JP;

Inventors:

Akihiro Fujii, Tokyo, JP;

Hiroshi Tanaka, Tokyo, JP;

Makio Otsuki, Tokyo, JP;

Takafumi Kawaguchi, Tokyo, JP;

Kouichi Oshita, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/437 ; A61K031/4409 ;
U.S. Cl.
CPC ...
Abstract

When used concurrently with an antitumor agent, a compound having a Rho kinase inhibitory activity, such as (R)-(+)-N-(4-pyridyl)-4-(1-aminoethyl)benzamide, reinforces an antitumor effect of the antitumor agent and is useful as an antitumor effect potentiator. Particularly, a compound having a Rho kinase inhibitory activity used with an antitumor agent in combination can reduce the dose of the antitumor agent, which in turn affords provision of a sufficient effect and/or reduction of side effects.


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