The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2005
Filed:
Dec. 16, 2002
Venkata B. Nanduri, East Brunswick, NJ (US);
Robert M. Johnston, Whitehouse Station, NJ (US);
Steven L. Goldberg, Basking Ridge, NJ (US);
Paul M. Cino, Bound Brook, NJ (US);
Ramesh N. Patel, Bridgewater, NJ (US);
Venkata B. Nanduri, East Brunswick, NJ (US);
Robert M. Johnston, Whitehouse Station, NJ (US);
Steven L. Goldberg, Basking Ridge, NJ (US);
Paul M. Cino, Bound Brook, NJ (US);
Ramesh N. Patel, Bridgewater, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
This invention relates to an novel2-ketoreductase useful for the synthesis of chiral alcohols. Also related are isolated nucleic acids encoding2-ketoreductase enzymes, and enzyme fragments and variants thereof, as well as vectors and host cells comprising these nucleic acids. Further related are isolated2-ketoreductase polypeptides, and fragments and variants thereof, and antibodies that specifically bind to2-ketoreductase polypeptides, fragments, or variants. The invention also relates to methods of obtaining isolated2-ketoreductase nucleic acids, polypeptides, and antibodies, and methods of using2-ketoreductase in various reactions for industrial or pharmaceutical applications.