The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2005

Filed:

Aug. 09, 2002
Applicants:

Robert F. Kaltenbach, Wilmington, DE (US);

Simon P. Robinson, Stow, MA (US);

George L. Trainor, Wilmington, DE (US);

Inventors:

Robert F. Kaltenbach, Wilmington, DE (US);

Simon P. Robinson, Stow, MA (US);

George L. Trainor, Wilmington, DE (US);

Assignee:

Bristol Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/24 ; C07C311/00 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides, inter alia, triphenylethylene derivatives, such as, 3-{4-[6-(3-Methoxy-phenyl)-8,9-dihydro-7H-benzocyclohepten-5-yl]-phenyl}-acrylic acid, as selective estrogen receptor modulators. Also provided are methods for the treatment and/or prevention of estrogen stimulated diseases in mammals including breast, uterine, ovarian, prostrate and colon cancer, osteoporosis, cardiovascular disease, and benign proliferative disorders, as well as pharmaceutical compositions of the compounds of the present invention.


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