The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2005

Filed:

Oct. 16, 2002
Applicants:

Frederick Earl Boyer, Jr., Canton Township, MI (US);

John Michael Domagala, Canton, MI (US);

Edmund Lee Ellsworth, Brighton, MI (US);

Christopher Andrew Gajda, Ann Arbor, MI (US);

Elizabeth Ann Lunney, Ann Arbor, MI (US);

Alexander Pavlovsky, Ann Arbor, MI (US);

Vara Prasad Venkata Nagendra Josyula, Ann Arbor, MI (US);

Bradley Dean Tait, Killingworth, CT (US);

Inventors:

Frederick Earl Boyer, Jr., Canton Township, MI (US);

John Michael Domagala, Canton, MI (US);

Edmund Lee Ellsworth, Brighton, MI (US);

Christopher Andrew Gajda, Ann Arbor, MI (US);

Elizabeth Ann Lunney, Ann Arbor, MI (US);

Alexander Pavlovsky, Ann Arbor, MI (US);

Vara Prasad Venkata Nagendra Josyula, Ann Arbor, MI (US);

Bradley Dean Tait, Killingworth, CT (US);

Assignee:

Warner-Lambert Company, Ann Arbor, MI (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D401/06 ; C07D401/04 ; C07D403/04 ; A61K031/351 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel dihydropyrones of Formula Iwherein X is NH or NR, which inhibit the HIV aspartyl protease blocking HIV infectivity. The dihydropyrones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS.


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