The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2005
Filed:
Jul. 28, 2003
Saeed R. Khan, Owings Mills, MD (US);
Bert Vogelstein, Baltimore, MD (US);
Kenneth W. Kinzler, Bel Air, MD (US);
Hallur Gurulingappa, Baltimore, MD (US);
Phillip Buckhaults, Columbia, SC (US);
Saeed R. Khan, Owings Mills, MD (US);
Bert Vogelstein, Baltimore, MD (US);
Kenneth W. Kinzler, Bel Air, MD (US);
Hallur Gurulingappa, Baltimore, MD (US);
Phillip Buckhaults, Columbia, SC (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
Aminophosphinic acid derivatives were synthesized as potential inhibitors of renal dipeptidase, an enzyme overexpressed in benign and malignant colon tumors. Several compounds showed potent enzyme-inhibitory activity. These compounds can be used therapeutically and diagnostically for treatment and detection of tumors.