The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2005
Filed:
Jun. 22, 2001
Thomas P. Kasten, O'Fallon, IL (US);
Mark G. Currie, Marlborough, MA (US);
William M. Moore, St. Charles, MO (US);
Kay Broschat, St. Louis, MO (US);
Thomas P. Kasten, O'Fallon, IL (US);
Mark G. Currie, Marlborough, MA (US);
William M. Moore, St. Charles, MO (US);
Kay Broschat, St. Louis, MO (US);
Pharmacia Corporation, St. Louis, MO (US);
Abstract
The present invention relates to a rapid high-throughput ion-exchange resin assay for determining enzyme activity. This novel assay uses a radiometric technique which separates the radioactive substrate from the product (or the radioactive product from the substrate) by exploiting the differences in the net charges of the molecules using ion-exchange resin. This assay is useful, for example, for studies of enzyme kinetics, the identification of functional sites in the enzyme, and in the automated screening of compound libraries for pharmaceutical drug development.