The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2005

Filed:

Sep. 28, 1999
Applicants:

Allan M. Miller, Boxford, MA (US);

Douglas A. Treco, Arlington, MA (US);

Richard F Selden, Wellesley, MA (US);

Inventors:

Allan M. Miller, Boxford, MA (US);

Douglas A. Treco, Arlington, MA (US);

Richard F Selden, Wellesley, MA (US);

Assignee:

Transkaryotic Therapies, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H021/04 ; C12N015/00 ;
U.S. Cl.
CPC ...
Abstract

The present invention is directed to a synthetic nucleic acid sequence which encodes a protein wherein at least one non-common codon or less-common codon is replaced by a common codon. The synthetic nucleic acid sequence can include a continuous stretch of at least 90 codons all of which are common codons.


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