The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2005
Filed:
Aug. 20, 2002
Applicant:
Roderick Joseph Sorenson, Ann Arbor, MI (US);
Inventor:
Roderick Joseph Sorenson, Ann Arbor, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/33 ; C07D331/00 ; C07D333/00 ; C07D317/00 ;
U.S. Cl.
CPC ...
Abstract
The invention provides dicarboxylic acid-substituted heteroaryl derivatives of the formulaG-(C(R)R)-Q-B-Q-(C(R)R)-G  Ior a pharmaceutically acceptable salt thereof, wherein G, G, R, R, R, R, n, m, Q, Q, and B are as defined in the specification. The invention compounds are inhibitors of matrix metalloproteinase enzymes, including MMP-13. This invention also provides pharmaceutical compositions and methods of treating diseases mediated by MMP-13, including arthritis, asthma, heart disease, atherosclerosis, and osteoporosis, or a pharmaceutically acceptable salt thereof.