The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 02, 2005

Filed:

Sep. 18, 2001
Applicants:

Marc A. R. C. Daemen, Sittard, NL;

Vincent H. Heemskerk, Maastricht, NL;

Cornelis Van't Veer, Meerssen, NL;

Geertrui Denecker, Veldegem, BE;

Tim G. A. M. Wolfs, Maastricht, NL;

Peter Vandenabeele, St-Amandsberg, BE;

Wim A. Buurman, Eijsden, NL;

Jaakko Parkkinen, Espoo, FI;

Inventors:

Marc A. R. C. Daemen, Sittard, NL;

Vincent H. Heemskerk, Maastricht, NL;

Cornelis van't Veer, Meerssen, NL;

Geertrui Denecker, Veldegem, BE;

Tim G. A. M. Wolfs, Maastricht, NL;

Peter Vandenabeele, St-Amandsberg, BE;

Wim A. Buurman, Eijsden, NL;

Jaakko Parkkinen, Espoo, FI;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K038/16 ; A01N001/00 ; C07K014/00 ;
U.S. Cl.
CPC ...
Abstract

The present invention comprises a method of protecting organs or tissue susceptible to reperfusion-induced dysfunction after ischemia. The method comprises parenterally administering to a patient a therapeutical composition containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or a mixture thereof. Alternatively, organ or tissue transplants can be contacted with natural alpha-1 acid glycoprotein, natural alpha-antitrypsin or mixtures by perfusing or flushing them with a solution containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or mixtures thereof in a concentration of 0.1 to 5 g/l.


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