The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2005
Filed:
Nov. 15, 2001
Applicants:
Cristina Di Bugno, Pisa, IT;
Fabio D'arata, Cascina, IT;
Alessio Ramacciotti, Leghorn, IT;
Paolo Crotti, Capannori, IT;
Inventors:
Cristina Di Bugno, Pisa, IT;
Fabio D'Arata, Cascina, IT;
Alessio Ramacciotti, Leghorn, IT;
Paolo Crotti, Capannori, IT;
Assignee:
Menarini Richerche S.p.A., Pomezio, IT;
Primary Examiner:
Int. Cl.
CPC ...
C07C045/00 ; C07C049/213 ; C07H001/00 ;
U.S. Cl.
CPC ...
Abstract
It is described a process for the synthesis of optically active anthracyclines by the fact that the key intermediate (R)2-acetyl-2-hydroxy-1,2,3,4-tetrahydronaphtalene 5,8-dialkoxy-3,4-dihydronaphtalene by acylation asymmetric dihydroxylation, transformation into chloroacetate, dehydrochloridation and final hydrolysis.