The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2005
Filed:
Jul. 31, 2001
Paul O. Zamora, Gaithersburg, MD (US);
Ray Tsang, Salt Lake City, UT (US);
Shigemasa Osaki, Sandy, UT (US);
Paul O. Zamora, Gaithersburg, MD (US);
Ray Tsang, Salt Lake City, UT (US);
Shigemasa Osaki, Sandy, UT (US);
BioSurface Engineering Technologies, Inc., College Park, MD (US);
Abstract
The present invention provides a bioactive coating composition, method and devices for bodily fluid-contacting surfaces. The coating comprises a complex of Formula II: wherein Ris an Calkyl or Caryl group, each Ris independently selected from the group consisting of Calkyl and Caryl, Ris N or O, n is a number from 1 to 10, and x in a number from 1 to about 30, directly bound to a heparin-activity molecule via covalent bonding, with one or more bioactive molecules bound to the heparin-activity molecule. The bioactive molecule may be an adhesive molecule such as fibronectin, a growth factor such as basic fibroblast growth factor, or any other bioactive molecule that binds, by any mechanism, to a heparin-activity molecule