The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 26, 2005

Filed:

Oct. 10, 2001
Applicants:

Neville J. Anthony, Hatfield, PA (US);

Robert P. Gomez, Perkasie, PA (US);

Steven D. Young, Lansdale, PA (US);

Melissa Egbertson, Ambler, PA (US);

John S. Wai, Harleysville, PA (US);

Linghang Zhuang, Chalfont, PA (US);

Mark Embrey, North Wales, PA (US);

Jeffrey Y. Melamed, Doylestown, PA (US);

H. Marie Langford, Lansdale, NJ (US);

James P. Guare, Quakertown, PA (US);

Thorsten E. Fisher, Hatfield, PA (US);

Samson M. Jolly, Quakertown, PA (US);

Michelle S. Kuo, Gwynedd Valley, PA (US);

Debra S. Perlow, East Greenville, PA (US);

Jennifer J. Bennett, East Norriton, PA (US);

Timothy W. Funk, Ephrata, PA (US);

Inventors:

Neville J. Anthony, Hatfield, PA (US);

Robert P. Gomez, Perkasie, PA (US);

Steven D. Young, Lansdale, PA (US);

Melissa Egbertson, Ambler, PA (US);

John S. Wai, Harleysville, PA (US);

Linghang Zhuang, Chalfont, PA (US);

Mark Embrey, North Wales, PA (US);

Jeffrey Y. Melamed, Doylestown, PA (US);

H. Marie Langford, Lansdale, NJ (US);

James P. Guare, Quakertown, PA (US);

Thorsten E. Fisher, Hatfield, PA (US);

Samson M. Jolly, Quakertown, PA (US);

Michelle S. Kuo, Gwynedd Valley, PA (US);

Debra S. Perlow, East Greenville, PA (US);

Jennifer J. Bennett, East Norriton, PA (US);

Timothy W. Funk, Ephrata, PA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P031/00 ; A61K031/4375 ; C07D471/02 ;
U.S. Cl.
CPC ...
Abstract

Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described. These compounds are inhibitors of HIV integrase and inhibitors of HIV replication, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of preventing, treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.


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