The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 2005
Filed:
Mar. 07, 2003
Thierry Dervieux, San Diego, CA (US);
Russell B. Richerson, Tucson, AZ (US);
Thierry Dervieux, San Diego, CA (US);
Russell B. Richerson, Tucson, AZ (US);
Prometheus Laboratories, Inc., San Diego, CA (US);
Abstract
The present invention provides a method for determining a level of a methotrexate polyglutamate (MTXPG) in a cellular extract by resolving at least one MTXPG in a cellular extract obtained from a human undergoing methotrexate therapy; and detecting at least one resolved MTXPG, thereby determining a level of the resolved MTXPG. A method of the invention can be useful, for example, for determining a level of MTXPG, MTXPGor MTXPGor for determining a level of each methotrexate polyglutamate species (MTXPGto MTXPG) present in the cellular extract.