The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2005
Filed:
May. 29, 2002
Kurt Hamacher, Aachen, DE;
Kurt Hamacher, Aachen, DE;
Forschungszentrum Jülich GmbH, Jülich, DE;
Abstract
The compound O-(2-[F]fluoroethyl)-L-tyrosine has proven to be particularly suitable for positron emission tomography and has already been tested in clinical practice. Until now, the compound has been prepared according to a relatively laborious method (Wester H. J. et al., J. Nucl. Med. 1999; 40: 205-212). The invention relates to L-tyrosine derivatives of the formula (1)whereby Rrepresents a suitable protective group for the carboxy group, Ra suitable protective group for the amino group and Ra suitable leaving group, The invention also relates to a method for preparing O-(2-[F]-fluoroethyl)-L-tyrosine from the initial compounds of formula (1) and method for the preparation of these initial compounds.