The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2005
Filed:
Jun. 20, 2003
Hashem Akhavan-tafti, Howell, MI (US);
Robert A. Eickholt, Troy, MI (US);
Kenneth S. Lauwers, Waterford, MI (US);
Richard S. Handley, Canton, MI (US);
Hashem Akhavan-Tafti, Howell, MI (US);
Robert A. Eickholt, Troy, MI (US);
Kenneth S. Lauwers, Waterford, MI (US);
Richard S. Handley, Canton, MI (US);
Lumigen, Inc., Southfield, MI (US);
Abstract
Compounds useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula:is reacted with peroxide. Sig is an aromatic or heteroaromatic ring group, B is a boron atom, and Rand Rare independently selected from hydrogen and lower alkyl groups and can be joined together as a straight or branched alkylene chain forming a five or six-membered ring. A detectable product compound of the formula Sig-OH Is produced and detected by measuring color, fluorescence, chemiluminescence, or bioluminescence. The signalling compound itself does not possess the detectable property or does so only to a very weak degree. The compounds can be used for detection in assays for peroxide or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs.