The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2005
Filed:
May. 20, 2003
Scott C. Benson, Alameda, CA (US);
Joe Y. L. Lam, Castro Valley, CA (US);
Steven Michael Menchen, Fremont, CA (US);
Scott C. Benson, Alameda, CA (US);
Joe Y. L. Lam, Castro Valley, CA (US);
Steven Michael Menchen, Fremont, CA (US);
Applera Corporation, Foster City, CA (US);
Abstract
Dibenzorhodamine compounds having the structureare disclosed, including nitrogen- and aryl-substituted forms thereof. In addition, two intermediates useful for synthesizing such compounds are disclosed, a first intermediate having the structureincluding nitrogen- and aryl-substituted forms thereof, and a second intermediate having the structureincluding nitrogen- and aryl-substituted forms thereof, wherein substituents at positions C-14 to C18 taken separately are selected from the group consisting of hydrogen, chlorine, fluorine, lower alkyl, carboxylic acid, sulfonic acid, —CHOH, alkoxy, phenoxy, linking group, and substituted forms thereof. The invention further includes energy transfer dyes comprising the dibenzorhodamine compounds, nucleosides labeled with the dibenzorhodamine compounds, and nucleic acid analysis methods employing the dibenzorhodamine compounds.