The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2005

Filed:

Jun. 28, 2001
Applicants:

Norio Fujiwara, Yao, JP;

Hitoshi Fujita, Takatsuki, JP;

Fujio Antoku, Nishinomiya, JP;

Toshinari Sugasawa, Nishinomiya, JP;

Hajime Kawakami, Nishinomiya, JP;

Inventors:

Norio Fujiwara, Yao, JP;

Hitoshi Fujita, Takatsuki, JP;

Fujio Antoku, Nishinomiya, JP;

Toshinari Sugasawa, Nishinomiya, JP;

Hajime Kawakami, Nishinomiya, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/425 ; C07P277/08 ; A61P029/00 ;
U.S. Cl.
CPC ...
Abstract

A 5-membered cyclic compound of the formula:wherein X is oxygen or sulfur, Ris hydrogen, substituted or unsubstituted alkyl, etc., Ris hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, etc., Yis a direct bond, substituted or unsubstituted alkylene, —CO(CH)—, etc., the wavy line means (E)-configuration or (Z)-configuration, Ris substituted or unsubstituted aryl, etc., Yis substituted or unsubstituted alkylene, etc., Ris hydrogen, substituted or unsubstituted alkanoyl, substituted or unsubstituted alkyl, etc., Ris hydrogen, etc., or a salt thereof, these compound being able to inhibit infiltration of leukocytes such as eosinophils and lymphocytes, by which being useful for the treatment of various kinds of inflammation.


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