The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2005

Filed:

Jun. 26, 2002
Applicants:

Daniel Dube, St-Lazare, CA;

Yves Girard, L'lle-Bizard, CA;

Dwight Macdonald, L'lle-Bizard, CA;

Anthony Mastracchio, Linden, NJ (US);

Michel Gallant, Montreal, CA;

Patrick Lacombe, Montreal, CA;

Denis Deschenes, Carson Dorval, CA;

Inventors:

Daniel Dube, St-Lazare, CA;

Yves Girard, L'lle-Bizard, CA;

Dwight MacDonald, L'lle-Bizard, CA;

Anthony Mastracchio, Linden, NJ (US);

Michel Gallant, Montreal, CA;

Patrick Lacombe, Montreal, CA;

Denis Deschenes, Carson Dorval, CA;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/47 ; C07D215/14 ;
U.S. Cl.
CPC ...
Abstract

8-arylquinolines of formula (I) wherein the aryl group at the 8-position contains a meta two atom bridge to an optionally substituted phenyl or pyridyl group, are PDE4 inhibitors useful to treat asthma, chronic bronchitis, chronic obstructive pulmonary disease, arthritis, respiratory distress syndrome, allergic rhinitis, neurogenic inflammation, pain, rheumatoid arthritis, and other diseases. R-Rand Ar are as in claim


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