The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2005

Filed:

Oct. 09, 2001
Applicants:

Kwen-jen Chang, Chapel Hill, NC (US);

Robert W. Mcnutt, Jr., Durham, NC (US);

Hugh O. Pettit, Cary, NC (US);

Michael J. Bishop, Durham, NC (US);

Inventors:

Kwen-Jen Chang, Chapel Hill, NC (US);

Robert W. McNutt, Jr., Durham, NC (US);

Hugh O. Pettit, Cary, NC (US);

Michael J. Bishop, Durham, NC (US);

Assignee:

Ardent Pharmaceuticals, Inc., Durham, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/44 ; A61K031/4965 ; A61K038/00 ; A61K031/445 ;
U.S. Cl.
CPC ...
Abstract

A method of reducing, treating or preventing drug-mediated respiratory depression, muscle rigidity, or nausea/vomiting in an animal, incident to the administration to said animal of a mixed delta/mu opioid agonist or a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effective amount of a delta receptor agonist compound. Preferred examples of such delta receptor agonist compound include diarylmethyl piperazine compounds and diarylmethyl piperidine compounds, and pharmaceutical compositions thereof, having utility in medical therapy for reducing respiratory depression associated with certain analgesics, such as mu opiates.


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