The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2005
Filed:
Oct. 28, 2002
David J. Chaplin, Watlington, GB;
Charles Manly Garner, Iii, Waco, TX (US);
Robert Ronald Kane, Waco, TX (US);
Kevin G. Pinney, Woodway, TX (US);
Joseph Anthony Prezioso, Boston, MA (US);
Klaus Edvardsen, Klampenborg, DK;
David J. Chaplin, Watlington, GB;
Charles Manly Garner, III, Waco, TX (US);
Robert Ronald Kane, Waco, TX (US);
Kevin G. Pinney, Woodway, TX (US);
Joseph Anthony Prezioso, Boston, MA (US);
Klaus Edvardsen, Klampenborg, DK;
Oxigene, Inc., Waltham, MA (US);
Baylor University, Waco, TX (US);
Abstract
Novel stilbenoid compounds and their prodrug forms are disclosed, which serve as potent vascular targeting agents useful for the treatment of solid tumor cancers and other diseases associated with unwanted neovascularization. The novel stilbenoid compounds are tubulin-binding stilbenoid analogs structurally related to combretastatin A-1 and combretastatin A-4. The prodrug forms serve as potent vascular targeting agents (VTAs) useful for the treatment of solid tumor cancers and diseases associated with retinal neovascularization.