The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2005
Filed:
Mar. 16, 1998
Helga Kahlert, Darmstadt, DE;
Hans-thomas Stüwe, Darmstadt, DE;
Helmut Fiebig, Darmstadt, DE;
Oliver Cromwell, Darmstadt, DE;
Wolf-meinhard Becker, Darmstadt, DE;
Albrecht Bufe, Darmstadt, DE;
Gabriele Schramm, Darmstadt, DE;
Lothar Jäger, Darmstadt, DE;
Wolf-dieter Müller, Darmstadt, DE;
Helga Kahlert, Darmstadt, DE;
Hans-Thomas Stüwe, Darmstadt, DE;
Helmut Fiebig, Darmstadt, DE;
Oliver Cromwell, Darmstadt, DE;
Wolf-Meinhard Becker, Darmstadt, DE;
Albrecht Bufe, Darmstadt, DE;
Gabriele Schramm, Darmstadt, DE;
Lothar Jäger, Darmstadt, DE;
Wolf-Dieter Müller, Darmstadt, DE;
Merck Patent Gesellschaft mit, Darmstadt, DE;
Abstract
The invention relates to modified recombinant allergen mutants which can be obtained from recombinant allergens which are derived from allergens which can be obtained by extraction from natural raw materials such as pollen of the speciesWhile these modified recombinant allergens stimulate lymphocytes from patients who are allergic to pollent to proliferate and synthesize cytokines, they exhibit a markedly diminished ability to bind to the IgE antibodies which are present in the serum of the T lymphocyte donors and to grass pollen allergen-specific IgEs and can therefore be used for a specific, made-to-release allergy therapy.