The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2005

Filed:

Apr. 15, 2002
Applicants:

Raf Lemmens, Uppsala, SE;

Tomas Nyhammar, Uppsala, SE;

Jan Berglof, Uppsala, SE;

Joachim Stadler, Freiburg, DE;

Inventors:

Raf Lemmens, Uppsala, SE;

Tomas Nyhammar, Uppsala, SE;

Jan Berglof, Uppsala, SE;

Joachim Stadler, Freiburg, DE;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H021/00 ; C07G037/00 ; C08G063/68 ; C08G069/14 ; C08G069/26 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to a process for separating nucleic acid molecules, preferably open circular and supercoiled plasmid DNA and RNA molecules from each other, comprising the steps of providing a solution comprising the molecules; adsorbing the molecules to adsorbing groups on a carrier; and optionally washing the column with a suitable solution. The present process is especially suitable for large-scale isolation of supercoiled ccc DNA to be used in gene therapy.


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