The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2005

Filed:

Jun. 05, 2001
Applicants:

DE Chao Yu, Foster City, CA (US);

Daniel R. Henderson, Palo Alto, CA (US);

Eric R. Schuur, Palo Alto, CA (US);

Inventors:

De Chao Yu, Foster City, CA (US);

Daniel R. Henderson, Palo Alto, CA (US);

Eric R. Schuur, Palo Alto, CA (US);

Assignee:

Cell Genesys, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H021/04 ; C12N015/74 ;
U.S. Cl.
CPC ...
Abstract

Enhancers which preferentially increase the transcription of cis-linked coding sequences in prostate cells are provided. Methods of using DNA constructs comprising the enhancers to control transcription of heterologous polynucleotides are also provided. Delivery vehicles comprising the enhancers and methods of using the vehicles are also provided. Adenovirus vectors in which one or more genes are under transcriptional control of the enhancers of the invention are also provided. Further provided are methods of using the adenovirus vectors of the invention to confer selective cytotoxicity in mammalian cells.


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