The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2005
Filed:
Feb. 24, 2003
Kuo-hsiung Lee, Chapel Hill, NC (US);
Yi Xia, Foster City, CA (US);
Zheng-yu Yang, Foster City, CA (US);
Kenneth F. Bastow, Chapel Hill, NC (US);
Sheng-chu Kuo, Tai Chung, TW;
Kuo-Hsiung Lee, Chapel Hill, NC (US);
Yi Xia, Foster City, CA (US);
Zheng-Yu Yang, Foster City, CA (US);
Kenneth F. Bastow, Chapel Hill, NC (US);
Sheng-Chu Kuo, Tai Chung, TW;
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Abstract
Compounds are described having a structure according to Formula I or Formula II:wherein: X is selected from the group consisting of O, NH, and S; Y is selected from the group consisting of O and S; m is from 1 to 3; n is from 1 to 5; Rand Rare each independently selected from the group consisting of H, hydroxy, lower alky, lower alkoxy, halo, amino, aminoalkyl, nitro, heteroaryl, —OC(═O)R, —O(C═O)OR; and —O(C═O)N(R); and Ris side chain such as an acetic acid side chain, where p is O to 4, Ris hydroxy, alkoxy or amino, and Ris H or lower alkyl, or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of cancer.