The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2005
Filed:
Apr. 15, 2004
Kyungae Lee, Guilford, CT (US);
Scott A. Mitchell, East Haven, CT (US);
Robert Ohliger, Madison, CT (US);
Luyan Zhang, Branford, CT (US);
He Zhao, Branford, CT (US);
Kevin S. Currie, North Branford, CT (US);
Kyungae Lee, Guilford, CT (US);
Scott A. Mitchell, East Haven, CT (US);
Robert Ohliger, Madison, CT (US);
LuYan Zhang, Branford, CT (US);
He Zhao, Branford, CT (US);
Kevin S. Currie, North Branford, CT (US);
Neurogen Corporation, Branford, CT (US);
Abstract
Substituted tetrahydroisoquinolines and related compounds are provided. Such compounds are ligands that may be used to modulate C5a receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological C5a receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies: