The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2005
Filed:
Oct. 18, 2001
Bertrand Merot, Volvic, FR;
Wilfrid Dieryck, Saint-Pathus, FR;
Philippe Lenee, Noumea, FR;
Michael Marden, Aulnay-sous-Bois, FR;
Veronique Gruber, Chamalieres, FR;
Renee-josee Pagnier, Le Kremlin-Bicetre, FR;
Sylvie Baudino, Orcines, FR;
Claude Poyart, Paris, FR;
Bertrand Merot, Volvic, FR;
Wilfrid Dieryck, Saint-Pathus, FR;
Philippe Lenee, Noumea, FR;
Michael Marden, Aulnay-sous-Bois, FR;
Veronique Gruber, Chamalieres, FR;
Renee-Josee Pagnier, Le Kremlin-Bicetre, FR;
Sylvie Baudino, Orcines, FR;
Claude Poyart, Paris, FR;
Institut National de la Sante et de Recherche Medicale, Paris Cedex, FR;
Meristern Therapeutics, Clermont-Ferrand, FR;
Abstract
A method for producing haemin proteins by (i) inserting into plant cells one or more nucleic acid molecules that each comprise at least one sequence coding for a protein component of an animal haemin protein capable of reversibly binding oxygen, or for a variant or portion of said protein component, and optionally a sequence coding for a selection agent; (ii) selecting cells containing nucleic acid coding for the protein component of the haemin protein; (iii) optionally propagating the transformed cells either in a culture or by regenerating whole transgenic or chimeric plants; and (iv) recovering and optionally purifying a haemin protein that includes a complex consisting of the protein or proteins coded for by said nucleic acid and at least one iron-containing porphyritic nucleus, or a plurality of such complexes.