The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2005
Filed:
Aug. 28, 2001
Roland E. Baron, Guilford, CT (US);
Natalie Sims, Fitzroy, AU;
Georgios Sabatakos, New Haven, CT (US);
Eric Nestler, Dallas, TX (US);
Jingshan Chen, Cheshire, CT (US);
Max Kelz, Penn Valley, PA (US);
Roland E. Baron, Guilford, CT (US);
Natalie Sims, Fitzroy, AU;
Georgios Sabatakos, New Haven, CT (US);
Eric Nestler, Dallas, TX (US);
Jingshan Chen, Cheshire, CT (US);
Max Kelz, Penn Valley, PA (US);
Yale University, New Haven, CT (US);
Abstract
The present invention is based on the discovery that overexpression of ΔFosB leads to bone formation and that ΔFosB expression inhibits adipogenesis. The present invention provides methods of identifying agents that modulate bone formation and adipogenesis. Moreover, the present invention provides methods for identifying genes that are modulated by ΔFosB and that modulates ΔFosB, osteogenesis, and adipogenesis.