The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2005
Filed:
Jun. 06, 2003
Yicheng LU, East Brunswick, NJ (US);
Zheng Zhang, Bellemead, NJ (US);
Nuri William Emanetoglu, Woodbury, NJ (US);
Masayori Inouye, New Brunswick, NJ (US);
Oleg Mirochnitchenko, East Brunswick, NJ (US);
Yicheng Lu, East Brunswick, NJ (US);
Zheng Zhang, Bellemead, NJ (US);
Nuri William Emanetoglu, Woodbury, NJ (US);
Masayori Inouye, New Brunswick, NJ (US);
Oleg Mirochnitchenko, East Brunswick, NJ (US);
Rutgers, The State University of New Jersey, New Brunswick, NJ (US);
University of Medicine and Dentistry of NJ, New Brunswick, NJ (US);
Abstract
The present invention provides the multifunctional biological and biochemical sensor technology based on ZnO nanostructures. The ZnO nanotips serve as strong DNA or protein molecule binding sites to enhance the immobilization. Patterned ZnO nanotips are used to provide conductivity-based biosensors. Patterned ZnO nanotips are also used as the gate for field-effect transistor (FET) type sensors. Patterned ZnO nanotips are integrated with SAW or BAW based biosensors. These ZnO nanotip based devices operate in multimodal operation combining electrical, acoustic and optical sensing mechanisms. The multifunctional biosensors can be arrayed and combined into one biochip, which will enhance the sensitivity and accuracy of biological and biochemical detection due to strong immobilization and multimodal operation capability. Such biological and biochemical sensor technology are useful in detection of RNA-DNA, DNA-DNA, protein-protein, protein-DNA and protein-small molecules interaction. It can be further applied for drug discovery, and for environmental monitoring and protection.