The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2005

Filed:

Nov. 30, 2001
Applicants:

Nitya Anand, Uttar Pradesh, IN;

Sanjay Jain, Pune, IN;

Neelima Sinha, Uttar Pradesh, IN;

Anita Chugh, New Delhi, IN;

Laxminarayan G. Hegde, New Delhi, IN;

Jang Bahadur Gupta, Haryana, IN;

Inventors:

Nitya Anand, Uttar Pradesh, IN;

Sanjay Jain, Pune, IN;

Neelima Sinha, Uttar Pradesh, IN;

Anita Chugh, New Delhi, IN;

Laxminarayan G. Hegde, New Delhi, IN;

Jang Bahadur Gupta, Haryana, IN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/496 ; C07D403/06 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to a novel 1,4-disubstituted piperazine derivatives of Formula I,and their pharmaceutically acceptable acid addition salts having excellent uro-selective α-adrenoceptor antagonistic activity exceeding those of previously described compounds. The compounds of the present invention hold promise for treating the symptoms of benign prostatic hyperplasia (BPH). The invention also relates to methods for making the novel compounds, pharmaceutical compositions containing the compounds, and method of treating the symptoms of benign prostatic hyperplasia using the compounds.


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