The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2005

Filed:

Jan. 17, 2002
Applicants:

Hiroshi Kayakiri, Osaka, JP;

Yoshito Abe, Ibaraki, JP;

Hitoshi Hamashima, Kyoto, JP;

Hitoshi Sawada, Ibaraki, JP;

Tsuyoshi Mizutani, Ibaraki, JP;

Teruo Oku, Osaka, JP;

Noritsugu Yamasaki, Hyogo, JP;

Osamu Onomura, Nagasaki, JP;

Masahiro Nishikawa, Niigata, JP;

Takahiro Hiramura, Niigata, JP;

Takafumi Imoto, Niigata, JP;

Inventors:

Hiroshi Kayakiri, Osaka, JP;

Yoshito Abe, Ibaraki, JP;

Hitoshi Hamashima, Kyoto, JP;

Hitoshi Sawada, Ibaraki, JP;

Tsuyoshi Mizutani, Ibaraki, JP;

Teruo Oku, Osaka, JP;

Noritsugu Yamasaki, Hyogo, JP;

Osamu Onomura, Nagasaki, JP;

Masahiro Nishikawa, Niigata, JP;

Takahiro Hiramura, Niigata, JP;

Takafumi Imoto, Niigata, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/34 ; C07D307/79 ;
U.S. Cl.
CPC ...
Abstract

A sulfonamide compound of the formula (I):R—SONHCO—A—X—R  (I)wherein Ris alky, alkenyl, alkynyl and the like; A is an optionally substitutedheteropolycyclic group except benzimidazolyl, indolyl, 4,7-dihydrobenzimidazolyland 2,3-dihydrobenzoxazinyl; X is alkylene, oxa, oxa(lower)alkylene and the like; and Ris optionally substituted aryl, substituted biphenylyl and the like, a salt thereof and a pharmaceutical composition comprising the same. The sulfonamide compound is effective for the diseases treatable based on their blood sugar level-depressing activity, cGMP-PDE (especially PDE-V)-inhibiting activity, smooth muscle relaxing activity, bronchodilating activity, vasodilating activity, smooth muscle cell suppressing activity, and antiallergic activity.


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