The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2005

Filed:

Jun. 25, 2001
Applicants:

Giuseppina Bestetti, Agrate Brianza, IT;

Simona Cali', Abbiategrasso, IT;

Daniela Ghisotti, Milan, IT;

Gaetano Orsini, Varese, IT;

Giancarlo Tonon, Milan, IT;

Gabriele Zuffi, Novata Milanese, IT;

Inventors:

Giuseppina Bestetti, Agrate Brianza, IT;

Simona Cali', Abbiategrasso, IT;

Daniela Ghisotti, Milan, IT;

Gaetano Orsini, Varese, IT;

Giancarlo Tonon, Milan, IT;

Gabriele Zuffi, Novata Milanese, IT;

Assignee:

Keryos SpA, Milan, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N015/00 ; C07H021/04 ;
U.S. Cl.
CPC ...
Abstract

Strains of genetically modified prokaryotic micro-organisms capable of expressing polypeptides having the enzyme activity of the enzymes uridine posphorylase (UdP) and purine nucleoside phosphorylase (PNP) are described; the strains in question can be used, both in the form of whole cells and in the form of crude or purified extracts, to catalyse transglycosylation reactions between a donor nucleoside and an acceptor base with particularly high yields. The associated plasmid vectors are also described.


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