The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2005
Filed:
Mar. 19, 2001
Jeffrey A. Hubbell, Concord, MA (US);
Chandrashekhar P. Pathak, Waltham, MA (US);
Amarpreet S. Sawhney, Newton, MA (US);
Neil P. Desai, Los Angeles, CA (US);
Syed F. A. Hossainy, Austin, TX (US);
Jeffrey A. Hubbell, Concord, MA (US);
Chandrashekhar P. Pathak, Waltham, MA (US);
Amarpreet S. Sawhney, Newton, MA (US);
Neil P. Desai, Los Angeles, CA (US);
Syed F. A. Hossainy, Austin, TX (US);
Novocell, Inc., Irvine, CA (US);
Abstract
This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as a 'glue' to cause more than one biological substance to adhere together, or as carriers for biologically active species. Several methods for forming these membranes are provided. Each of these methods utilizes a polymerization system containing water-soluble macromers, species, which are at once polymers and macromolecules capable of further polymerization. The macromers are polymerized using a photoinitiator (such as a dye), optionally a cocatalyst, optionally an accelerator, and radiation in the form of visible or long wavelength UV light. The reaction occurs either by suspension polymerization or by interfacial polymerization. The polymer membrane can be formed directly on the surface of the biological material, or it can be formed on material, which is already encapsulated.