The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2005
Filed:
Dec. 23, 2002
Wolfgang Skranc, Vienna, AT;
Peter Poechlauer, Linz, AT;
Irma Wirth, Enns, AT;
Rudolf Neuhofer, Mittertreffling, AT;
Herbert Mayrhofer, Engerwitzdorf, AT;
Wolfgang Skranc, Vienna, AT;
Peter Poechlauer, Linz, AT;
Irma Wirth, Enns, AT;
Rudolf Neuhofer, Mittertreffling, AT;
Herbert Mayrhofer, Engerwitzdorf, AT;
DSM Fine Chemicals Austria NFG GmbH & CO KG, Linz, AT;
Abstract
A process for preparing protected, enantiomer-enriched cyanohydrins of the formulawhere R1 and R2 independently of one another can be an unsubstituted, monosubstituted or polysubstituted C-C-alkyl, C-C-aryl, C-C-heteroaryl, C-C-alkaryl, C-C-alkylheteroaryl or C-C-aralkyl radical or an unsubstituted, monosubstituted or polysubstituted C-C-heterocycle, or C-C-alkylheterocycle or together can be an unsubstituted or substituted C-C-alkylene radical, which can contain one or more heteroatoms in the chain, or one of the radicals is hydrogen, and R3 can be an unsubstituted or substituted C-C-alkyl, C-C-aryl or C-C-heteroaryl radical, by reacting an aldehyde or ketone of the formulawhere R1 and R2 are defined as above, in the presence of an (R)- or (S)-hydroxynitrile lyase in an organic, aqueous or 2-phase system or in emulsion at a temperature of −5 to +40° C. with a carbonic ester nitrile of the formulawhere R3 is defined as above.