The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6906204 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 14, 2005

Filed:

Nov. 14, 2002
Applicants:

Kwang-hyeg Lee, Gyeonggi-do, KR;

Jin-wan Kim, Seoul, KR;

Kwang-do Choi, Gyeonggi-do, KR;

Sang-ho Lee, Gyeonggi-do, KR;

Hong-suk Cho, Gyeonggi-do, KR;

Inventors:

Kwang-hyeg Lee, Gyeonggi-do, KR;

Jin-wan Kim, Seoul, KR;

Kwang-do Choi, Gyeonggi-do, KR;

Sang-ho Lee, Gyeonggi-do, KR;

Hong-suk Cho, Gyeonggi-do, KR;

Assignee:

CJ Corp., Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D309/10 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to a processing method for preparing lovastatin and simvastatin which comprises the steps of (1) performing lactonization of mevinic acid and its homologous compounds in the presence of a mixed organic solvent without an acid catalyst through nitrogen sweep; and (2) making crystals. In the process of the present invention, lovastatin and simvastatin highly purified can be produced in a high yield and especially, heterodimers formed as a by-product can be reduced remarkably. Therefore, the processing method of the present invention can be convenient and economical.


Find Patent Forward Citations

Lee, Kwang-hyeg. (2005). Processing method of lactionization in the preparation of statins (U.S. Patent No. 6906204). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6906204

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