The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2005
Filed:
Jan. 05, 1999
Peter Scott Dragovich, San Diego, CA (US);
Stephen Evan Webber, San Diego, CA (US);
Thomas Jay Prins, Cardiff, CA (US);
RU Zhou, Carlsbad, CA (US);
Joseph Timothy Marakovits, Encinitas, CA (US);
Theodore O. Johnson, Jr., San Diego, CA (US);
Jayashree Girish Tikhe, San Diego, CA (US);
Peter Scott Dragovich, San Diego, CA (US);
Stephen Evan Webber, San Diego, CA (US);
Thomas Jay Prins, Cardiff, CA (US);
Ru Zhou, Carlsbad, CA (US);
Joseph Timothy Marakovits, Encinitas, CA (US);
Theodore O. Johnson, Jr., San Diego, CA (US);
Jayashree Girish Tikhe, San Diego, CA (US);
Agouron Pharmaceuticals, Inc., San Diego, CA (US);
Abstract
Peptido and peptidomimetic compounds of the formula:wherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.