The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2005
Filed:
Dec. 06, 2002
Hiroki Tanaka, Arai, JP;
LI Rui Pan, Arai, JP;
Kiyoshi Ikura, Arai, JP;
Daicel Chemical Industries, Ltd, Osaka, JP;
Abstract
A process produces an optically active amine or its salt and includes the steps of reacting a ketone of Formula (1a)wherein Ris typically an unsubstituted or substituted hydrocarbon group; and Ris typically a hydrocarbon group having at least one oxo group and optionally having other substituent, with an optically active amine of Formula (2):wherein Ris an unsubstituted or substituted aryl group; Ris an unsubstituted or substituted lower alkyl group; and Cis an asymmetric carbon atom, in the presence of an organic acid to thereby yield a corresponding optically active imine, hydrogenating the imine in the presence of a catalyst to yield a corresponding amine, subjecting the amine or its salt to hydrogenolysis in the presence of a catalyst, and reducing the hydrogenolyzed product with a reducing agent.