The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2005

Filed:

Jul. 18, 2002
Applicants:

J. Phillip Bowen, Hull, GA (US);

Thomas Philip Robinson, Durham, NC (US);

Tedman Ehlers, Athens, GA (US);

David Goldsmith, Atlanta, GA (US);

Jack Arbiser, Atlanta, GA (US);

Inventors:

J. Phillip Bowen, Hull, GA (US);

Thomas Philip Robinson, Durham, NC (US);

Tedman Ehlers, Athens, GA (US);

David Goldsmith, Atlanta, GA (US);

Jack Arbiser, Atlanta, GA (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/12 ; C07C049/213 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present invention also relates to the use of chalcone and its analogs as antitumor/anticancer agents and to treat a number of conditions or disease states in which angiogenesis is a factor, including angiongenic skin diseases such as psoriasis, acne, rosacea, warts, eczema, hemangiomas, lymphangiogenesis, among numerous others, as well as chronic inflammatory disease such as arthritis.


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