The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2005
Filed:
May. 08, 2001
Nicole Chantel Barvian, Ann Arbor, MI (US);
Patrick Michael O'brien, Stockbridge, MI (US);
William Chester Patt, Chelsea, MI (US);
Joseph Armand Picard, Canton, MI (US);
Drago Robert Sliskovic, Saline, MI (US);
Nicole Chantel Barvian, Ann Arbor, MI (US);
Patrick Michael O'Brien, Stockbridge, MI (US);
William Chester Patt, Chelsea, MI (US);
Joseph Armand Picard, Canton, MI (US);
Drago Robert Sliskovic, Saline, MI (US);
Warner-Lambert Company, Morris Plains, NJ (US);
Abstract
The present invention provides compounds of formula (I) wherein R, Z, Y, W, R, V, and X are as defined in the description, and pharmaceutically acceptable salts thereof, which are useful for the treatment of diseases responsive to the inhibition of the enzyme 15-lipoxygenase. Thus, the compounds of formula (I) and their pharmaceutically acceptable salts are useful for treating diseases with an inflammatory component, including atherosclerosis, diseases involving chemotaxis of monocytes, inflammation, stroke, coronary artery disease, asthma, arthritis, colorectal cancer, and psoriasis.