The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2005
Filed:
Feb. 20, 2003
Takashi Ogino, Osaka, JP;
Yukari Konishi, Hyogo, JP;
Kunihiko Higashiura, Hyogo, JP;
Kazuhito Furukawa, Hyogo, JP;
Takashi Ogino, Osaka, JP;
Yukari Konishi, Hyogo, JP;
Kunihiko Higashiura, Hyogo, JP;
Kazuhito Furukawa, Hyogo, JP;
Nippon Zoki Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
A 2-phenylpiperazine derivative represented by the formula (I) or a pharmaceutically acceptable salt, hydrate, or complex thereof:wherein each of Xand Xis oxygen or two hydrogen atoms, XO, NH, NCH, or CH, n is an integer of 0 or 1, Ris hydrogen or lower alkyl and Ris hydrogen, cyano, tetrazolyl, aminotriazolyl , mesyl, t-butoxycarbonyl, or a lower alkyl which may be optionally substituted, Ris hydrogen, halogen, lower alkyl or lower alkoxy, each of Rand Ris hydrogen, lower alkoxy or trifluoromethyl, and a broken line indicates a single or double bond. The derivative may be used as a tachykinin antagonist in the treatment of diseases of the digestive system, nervous system and respiratory system, inflammation, allergy, carcinoid syndrome, chronic pain, headache, Crohn disease, depression and vomiting.