The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2005
Filed:
Jun. 03, 2003
Applicants:
Bernd Peschke, Malov, DK;
Rolf Hohlweg, Kvistgaard, DK;
Inventors:
Bernd Peschke, Malov, DK;
Rolf Hohlweg, Kvistgaard, DK;
Assignee:
Novo Nordisk A/S, Bagsvaerd, DK;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N043/00 ; A01N043/58 ; A61K031/55 ; C07D487/00 ; C07D401/00 ;
U.S. Cl.
CPC ...
Abstract
Novel substituted hexahydropyrrolo[1,2-a]pyrazines, octahydropyrido[1,2-a]-pyrazines and decahydropyrazino[1,2-a]azepines, use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, and a method of treatment employing these compounds and compositions. The compounds show a high and selective binding affinity to the histamine H3 receptor indicating histamine H3 receptor antagonistic, inverse agonistic or agonistic activity. As a result, the compounds are useful for the treatment of diseases and disorders related to the histamine H3 receptor.