The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2005
Filed:
Feb. 10, 2003
Yinon Ben-neriah, Mevasseret Zion, IL;
Irit Alkalay-snir, Zur Hadassah, IL;
Ada Hatzubai, Kibutz Tzuba, IL;
Etti Ben Shushan, Akiva, IL;
Matti Davis, Modiin, IL;
Avraham Yaron, Jerusalem, IL;
Yinon Ben-Neriah, Mevasseret Zion, IL;
Irit Alkalay-Snir, Zur Hadassah, IL;
Ada Hatzubai, Kibutz Tzuba, IL;
Etti Ben Shushan, Akiva, IL;
Matti Davis, Modiin, IL;
Avraham Yaron, Jerusalem, IL;
Abstract
Compounds that inhibit ubiquitin-mediated proteolysis of phosphorylated IκB by interfering, directly or indirectly, with the ability of β-TrCP/E3RS to engage in protein-protein association involving hnRNP-U, are useful as drugs for treating conditions associated with NF-κB activation. Cellular and non-cellular screening methods for identifying such compounds are based on monitoring the association/dissociation of β-TrCP/E3RS.