The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2005
Filed:
Nov. 13, 2001
Applicants:
Menzo Jans Emco Havenga, Alphen a/d Rijn, NL;
Abraham Bout, Moerkapelle, NL;
Ronald Vogels, Linschoten, NL;
Inventors:
Menzo Jans Emco Havenga, Alphen a/d Rijn, NL;
Abraham Bout, Moerkapelle, NL;
Ronald Vogels, Linschoten, NL;
Assignee:
Crucell Holland B.V., Leiden, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N063/00 ; C12N015/00 ; C12N005/00 ; C12N021/06 ; C12N015/63 ;
U.S. Cl.
CPC ...
Abstract
Methods and associated materials for transducing mesenchymal stem cells with a desired nucleic acid. Mesenchymal stem cells are a recently discovered kind of stem cell for which suitable transfer vehicles are still desired. Typical gene delivery vehicles such as the adenoviruses or adeno associated viruses have no particular tropism for mesenchymal stem cells. Also disclosed is gene therapy using adenoviruses provided with tropism for mesenchymal stem cells.