The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2005
Filed:
Jul. 01, 1999
Steven M. Ruben, Olney, MD (US);
Pablo Jimenez, Ellicott City, MD (US);
D. Roxanne Duan, Bethesda, MD (US);
Mark A. Rampy, Gaithersburg, MD (US);
Donna Mendrick, Mt. Airy, MD (US);
Jun Zhang, Bethesda, MD (US);
Jian NI, Rockville, MD (US);
Paul A. Moore, Germantown, MD (US);
Timothy A. Coleman, Gaithersburg, MD (US);
Joachim R. Gruber, Chestnut Hill, MA (US);
Patrick J. Dillon, Carlsbad, CA (US);
Reiner L. Gentz, Rockville, MD (US);
Steven M. Ruben, Olney, MD (US);
Pablo Jimenez, Ellicott City, MD (US);
D. Roxanne Duan, Bethesda, MD (US);
Mark A. Rampy, Gaithersburg, MD (US);
Donna Mendrick, Mt. Airy, MD (US);
Jun Zhang, Bethesda, MD (US);
Jian Ni, Rockville, MD (US);
Paul A. Moore, Germantown, MD (US);
Timothy A. Coleman, Gaithersburg, MD (US);
Joachim R. Gruber, Chestnut Hill, MA (US);
Patrick J. Dillon, Carlsbad, CA (US);
Reiner L. Gentz, Rockville, MD (US);
Human Genome Sciences, Inc., Rockville, MD (US);
Abstract
This invention relates to newly identified polynucleotides, polypeptides encoded by such polynucleotides, the use of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides. More particularly, the polypeptide of the present invention is a Keratinocyte Growth Factor, sometimes hereinafter referred to as 'KGF-2' also formerly known as Fibroblast Growth Factor 12 (FGF-12). This invention further relates to the therapeutic use of KGF-2 to promote or accelerate wound healing. This invention also relates to novel mutant forms of KGF-2 that show enhanced activity, increased stability, higher yield or better solubility.