The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2005
Filed:
Dec. 15, 2000
Ali Laayoun, Lyons, FR;
Lionel Menou, Lyons, FR;
Christelle Tora, Lyons, FR;
Aloke R. Banerjee, San Diego, CA (US);
Michael M. Becker, San Diego, CA (US);
Kenneth A. Browne, San Diego, CA (US);
Matthew C. Friedenberg, San Diego, CA (US);
Fred F. Hajjar, San Diego, CA (US);
Ali Laayoun, Lyons, FR;
Lionel Menou, Lyons, FR;
Christelle Tora, Lyons, FR;
Aloke R. Banerjee, San Diego, CA (US);
Michael M. Becker, San Diego, CA (US);
Kenneth A. Browne, San Diego, CA (US);
Matthew C. Friedenberg, San Diego, CA (US);
Fred F. Hajjar, San Diego, CA (US);
Bio Merieux, Marcy l' Etoile, FR;
Gen-Probe Incorporated, San Diego, CA (US);
Abstract
A process of fragmenting and labeling a synthetic or natural nucleic acid, comprising the steps of providing a mixture containing a nucleic acid, a labeling agent containing a detectable label, and at least one multivalent metal cation in a substantially aqueous solution; chemically fragmenting the nucleic acid in the mixture to produce a multiplicity of nucleic acid fragments; and attaching at least one label to at least one of the nucleic acid fragments to produce a detectably labeled nucleic acid fragment.