The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2005
Filed:
Apr. 06, 1998
Jean A. Setterstrom, Alpharetta, GA (US);
Thomas R. Tice, Birmingham, AL (US);
Elliot Jacob, Silver Spring, MD (US);
Robert H. Reid, Kensington, MD (US);
John Van Hamont, West Point, NY (US);
Edgar C. Boedecker, Crownsville, MD (US);
Ramassubbu Jeyanthi, Columbia, MD (US);
Phil Friden, Bedford, MA (US);
F. Donald Roberts, Dover, MA (US);
Charles E. Mcqueen, Olney, MD (US);
Apurba Bhattacharjee, Kensington, MD (US);
Alan Cross, Chevy Chase, MD (US);
Jerald Sadoff, Washington, DC (US);
Wendell Zollinger, Silver Spring, MD (US);
Jean A. Setterstrom, Alpharetta, GA (US);
Thomas R. Tice, Birmingham, AL (US);
Elliot Jacob, Silver Spring, MD (US);
Robert H. Reid, Kensington, MD (US);
John van Hamont, West Point, NY (US);
Edgar C. Boedecker, Crownsville, MD (US);
Ramassubbu Jeyanthi, Columbia, MD (US);
Phil Friden, Bedford, MA (US);
F. Donald Roberts, Dover, MA (US);
Charles E. McQueen, Olney, MD (US);
Apurba Bhattacharjee, Kensington, MD (US);
Alan Cross, Chevy Chase, MD (US);
Jerald Sadoff, Washington, DC (US);
Wendell Zollinger, Silver Spring, MD (US);
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Abstract
Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1-100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer having a molar composition of lactide/glycolide from 90/10 to 40/60, which may contain a pharmaceutically-acceptable adjuvant, as a blend of uncapped free carboxyl end group and end-capped forms ranging to ratios from 100/0 to 1/99.