The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2005
Filed:
Sep. 27, 2001
Dalia Cohen, Livingston, NJ (US);
Uwe Jochen Dengler, Loerrach, DE;
Alyce Lynn Finelli, Parsippany, NJ (US);
Felix Freuler, Riehen, CH;
Mary Konsolaki, Westfield, NJ (US);
Mischa Werner Henri Marie Reinhardt, Bantzenheim, FR;
Susan Zusman, Sudbury, MA (US);
Dalia Cohen, Livingston, NJ (US);
Uwe Jochen Dengler, Loerrach, DE;
Alyce Lynn Finelli, Parsippany, NJ (US);
Felix Freuler, Riehen, CH;
Mary Konsolaki, Westfield, NJ (US);
Mischa Werner Henri Marie Reinhardt, Bantzenheim, FR;
Susan Zusman, Sudbury, MA (US);
Novartis, East Hanover, NJ (US);
Abstract
Transgenic flies displaying altered phenotypes due to expression of the Abeta and C99 portions of the human APP gene are disclosed. Use of these flies in a method to identifygenes and the human homologs of thesegenes, that are potentially involved in Alzheimer's Disease, is also disclosed. The use of said human homologs as drug targets for the development of therapeutics to treat Alzheimer's Disease and other conditions associated with defects in the APP pathway, as well as pharmaceutical compositions comprising substances directed to these genes, are also disclosed.