The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2005
Filed:
Jul. 16, 2002
Todd Richard Elworthy, Los Gatos, CA (US);
Tara Mirzadegan, Los Altos, CA (US);
Michael Garret Roepel, San Francisco, CA (US);
David Bernard Smith, San Mateo, CA (US);
Keith Adrian Walker, Los Altos Hills, CA (US);
Todd Richard Elworthy, Los Gatos, CA (US);
Tara Mirzadegan, Los Altos, CA (US);
Michael Garret Roepel, San Francisco, CA (US);
David Bernard Smith, San Mateo, CA (US);
Keith Adrian Walker, Los Altos Hills, CA (US);
Syntex (U.S.A.) LLC, Palo Alto, CA (US);
Abstract
This invention relates to compounds which are generally EPreceptor agonists and which are represented by Formula I:wherein A is a —CH—CH—, or —CH═CH—; B is absent, an aryl, or heteroaryl group; Ris alkyl, alkenyl, alkynyl, cycloalkylalkyl, heterocyclylalkyl, aryl, arylalkyl or heteroaryl, when B is aryl or heteroaryl and R, R, Rand Rare not simultaneously hydrogen, or Ris heterocyclylalkyl, aryl, or heteroaryl when B is absent and R, R, Rand Rare simultaneously hydrogen; and the other substituents are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and methods of preparation thereof.