The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2005
Filed:
Nov. 09, 2000
Timothy Norris, Gales Ferry, CT (US);
Jeffrey W. Raggon, North Stonington, CT (US);
Richard D. Connell, East Lyme, CT (US);
James D. Moyer, East Lyme, CT (US);
Michael J. Morin, Waterford, CT (US);
Shama M. Kajiji, Mystic, CT (US);
Barbara A. Foster, Mystic, CT (US);
Karen J. Ferrante, East Greenwich, RI (US);
Sandra L. Silberman, Randolph, NJ (US);
Timothy Norris, Gales Ferry, CT (US);
Jeffrey W. Raggon, North Stonington, CT (US);
Richard D. Connell, East Lyme, CT (US);
James D. Moyer, East Lyme, CT (US);
Michael J. Morin, Waterford, CT (US);
Shama M. Kajiji, Mystic, CT (US);
Barbara A. Foster, Mystic, CT (US);
Karen J. Ferrante, East Greenwich, RI (US);
Sandra L. Silberman, Randolph, NJ (US);
OSI Pharmaceuticals, Inc., Melville, NY (US);
Abstract
The present invention relates to a stable crystalline form of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride designated the B polymorph, its production in essentially pure form, and its use. The invention also relates to the pharmaceutical compositions containing the stable polymorph B form of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine as hydrochloride, as well other forms of the compound, and to methods of treating hyperproliferative disorders, such as cancer, by administering the compound.