The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2005
Filed:
Jan. 02, 2002
Cyrus Kephra Becker, Menlo Park, CA (US);
Joan Marie Caroon, Mountain View, CA (US);
Chris Richard Melville, Palo Alto, CA (US);
Fernando Padilla, Fremont, CA (US);
Jürg Roland Pfister, Los Altos, CA (US);
Xiaoming Zhang, Campbell, CA (US);
Cyrus Kephra Becker, Menlo Park, CA (US);
Joan Marie Caroon, Mountain View, CA (US);
Chris Richard Melville, Palo Alto, CA (US);
Fernando Padilla, Fremont, CA (US);
Jürg Roland Pfister, Los Altos, CA (US);
Xiaoming Zhang, Campbell, CA (US);
Syntex (U.S.A.) LLC, Palo Alto, CA (US);
Abstract
This invention relates to compounds which are generally alpha-1A/B adrenoceptor antagonists and which are represented by Formula I:wherein Z is —C(O)— or —S(O)—, X is carbon or nitrogen, Y is carbon, and X—Y considered together are two adjoining atoms of the ring A, said ring being a fused aromatic ring of five to six atoms per ring optionally incorporating one to two heteroatoms per ring, chosen from N, O, or S; and the other substituents are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and methods of preparation thereof.